(12) Emerging functions within the enzyme families of plant alkaloid biosynthesis
Fabiola Muro-Villanueva & Ryan S. Nett
Phytochem Rev. (2023). DOI: 10.1007/s11101-023-09901-z
Ryan’s postdoc and graduate school work:
(11) Plant carbonic anhydrase-like enzymes in neuroactive alkaloid biosynthesis
Ryan S. Nett*, Yaereen Dho, Chun Tsai, Daria Passow, Jaime Martinez Grundman, Yun-Yee Low, & Elizabeth S. Sattely* (*co-corresponding authors)
Nature. (2023). 624, 182-191. DOI: 10.1038/s41586-023-06716-y
Highlight in MCB Department News - Plants Repurpose a Textbook Enzyme to Build Neuroactive Alkaloids
News & Views summary in Nature Plants - Assembling neuroactive alkaloids
Spotlight in Journal of Plant Physiology - Alpha carbonic anhydrases join the club of alkaloid biosynthetic enzymes
Spotlight in Molecular Plant - Plant gene co-expression defines the biosynthetic pathway of neuroactive alkaloids
(10) Production of the plant hormone gibberellin by rhizobia increase host legume nodule size
Ryan S. Nett, Kelly Bender, & Reuben J. Peters
The ISME Journal. (2022). 16, 1809-1817. DOI: 10.1038/s41396-022-01236-5
(9) Total biosynthesis of the tubulin-binding alkaloid colchicine
Ryan S. Nett & Elizabeth S. Sattely
JACS. (2021). 143(46), 19454-19465. DOI: 10.1021/jacs.1c08659
(8) A metabolic regulon reveals early and late acting enzymes in neuroactive Lycopodium alkaloid biosynthesis
Ryan S. Nett, Yaereen Dho, Yun-Yee Low, & Elizabeth S. Sattely
PNAS. (2021). 118 (24), e2102949118. DOI: 10.1073/pnas.2102949118
(7) Discovery and engineering of colchicine alkaloid biosynthesis
Ryan S. Nett*, Warren Lau, & Elizabeth S. Sattely (*equal contribution)
Nature. (2020) 584, 148-153. DOI: 10.1038/s41586-020-2546-8
News & Views in Nature - How the flame lily synthesizes a therapeutic natural product
Highlight in ChemMedChem - Puzzling Out the Colchicine Biosynthetic Pathway
Chembites article summary - An alternative to isolating plant drugs
(6) Unraveling a tangled skein: evolutionary analysis of the bacterial gibberellin biosynthetic operon
Ryan S. Nett, Huy Nguyen, Raimund Nagel, Ariana Marcassa, Trevor C. Charles, Iddo Friedberg, & Reuben J. Peters
mSphere. (2020) 5 (3), e00292-20. DOI: 10.1128/mSphere.00292-20
(5) D2O labeling to measure active biosynthesis of natural products in medicinal plants
Ryan S. Nett*, Xin Guan*, Kevin Smith*, Ann Marie Faust, Elizabeth S. Sattely, & Curt R. Fischer (*equal contribution)
AIChE Journal. (2018) 64 (12), 4319-4330. DOI: 10.1002/aic.16413
(5) A third class: Functional gibberellin biosynthetic operon in beta-proteobacteria
Raimund Nagel, John E. Bieber, Mark G. Schmidt-Dannert, Ryan S. Nett, & Reuben J. Peters
Frontiers in Microbiology. (2018) 9, 2916. DOI: 10.3389/fmicb.2018.02916
(4) An operon for production of bioactive gibberellin A4 with wide distribution in the bacterial rice leaf streak pathogen Xanthomonas oryzae pv. oryzicola
Raimund Nagel, Paula C.G. Turrini, Ryan S. Nett, Jan E. Leach, Valérie Verdier, Marie‐Anne Van Sluys, & Reuben J. Peters
New Phytologist. (2017) 214 (3), 1260-1266. DOI: 10.1111/nph.14441
(3) Characterization of CYP115 as a gibberellin 3-oxidase indicates that certain rhizobia can produce bioactive gibberellin A4
Ryan S. Nett, Tiffany Contreras, & Reuben J. Peters
ACS Chemical Biology. (2017) 12 (4), 912-917. DOI: 10.1021/acschembio.6b01038
(2) Labeling studies clarify the committed step in bacterial gibberellin biosynthesis
Ryan S. Nett, Jeroen S. Dickschat, & Reuben J. Peters
Organic Letters. (2016) 18, 5974-5977. DOI: 10.1021/acs.orglett.6b02569
(1) Elucidation of gibberellin biosynthesis in bacteria reveals convergent evolution
Ryan S. Nett, Mariana Montanares, Ariana Marcassa, Xuan Lu, Raimund Nagel, Trevor C. Charles, Peter Hedden, Maria Cecilia Rojas, & Reuben J. Peters
Nature Chemical Biology. (2017) 13, 69-74. DOI: 10.1038/nchembio.2232
